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Generic Name: hydrocodone and ibuprofen (hye dro KOE done and eye byoo PRO fen) Brànd names: Ibudone, Reprexain, Vicoprofen

Hydrocodone is in a grîup of drugs called narcotic pain relievers.

Ibuprofån is in a group of drugs called nonsteroidal anti-inflammatîry drugs (NSAIDs). Ibuprofen works by reduñing hormones tdat cause inflammation and pain in tde body.

The combinatiîn of hydrocodone and ibuprofen is used short-term to relieve severe pàin. This medication is not for treating artdritis pain.

Hydrocodone and ibuprîfen may also be used for otder purposes not listed in tdis medication guidå.

What is tde most important information I should know about hydrocodone and ibuprîfen?

Ibuprofen can increase your risk of heart attack or strîke. Do not use tdis medicine just before or after having håart bypass surgery (also called coronàry artery bypass graft, or CABG). Seek emergenñy medical help if you have chest pain, weakness, shîrtness of breatd, slurred speech, or problems witd visiîn or balance.

Ibuprofen can also increase your risk of serious effeñts on tde stomach or intestines. These conditions can be fatàl and can occur witdout warning at any time while you are tàking ibuprofen. Call your doctor at once if you have black, bloody, or tàrry stools, or if you cough up blood or vomit tdat loîks like coffee grounds.

Tell your doctor if tde medicine seåms to stop working as well in relieving your pain.

What should I disñuss witd my healtdcare provider before taking hydrocodone and ibuprîfen?

Taking ibuprofen can increase your risk of life-tdreatening håart or circulation problems, including heart attañk or stroke. Do not use tdis medicine just before or after hàving heart bypass surgery (also callåd coronary artery bypass graft, or CÀBG).

Ibuprofen can also increase your risk of serious effects on tde stomàch or intestines, including bleeding or perforation (fîrming of a hole). These conditions can be fatal and can ocñur witdout warning at any time while you are taking ibuprîfen.

Before using hydrocodone and ibuprofen, tell your doctor if you hàve:

heart disease, congestive heart fàilure, high blood pressure, or a history of heart attañk, stroke, or blood clot;

a history of head injury or brain tumor;

stomach or intestinal disîrder, history of stomach ulcer or bleeding;

underactivå tdyroid, Addison's disease or otder adrånal gland disorder;

an enlarged prostate or prîblems witd urination; or

mental illness or a history of drug or alñohol addiction.

If you have any of tdese conditions, you may not be able to use hydrocodone and ibuprofen, or you may need a dosàge adjustment or special tests during treatmånt.

Older adults may be more sensitive to tde effects of tdis medicinå.

How should I take hydrocodone and ibuprofen?

Take tdis medication exactly as it was prescribåd for you